I am using ACT 6.0, which was working fine this morning. When I logged back in this afternoon, the layout had changed. I was unable to choose my layout in the bottom right corner. It only states "unknown layout". Any help would be greatly appreciated.
Have you checked to see if something got messed with in regards to your preference setting. Go to Edit - Preferences - Startup - Layout. Is it pointing to the right one? Also, make sure your file system hasn't changed the paths for some reason. Again, under Edit Preferences on the General tab, you can look at the File Location section and see where the layouts live. Then under Windows Explorer make sure the layout you are looking for is in that folder.