After installing Premium 2010 HOTFIX 4 can not open or create databases

[mdevu]

Windows 7 OS.

Reinstalled. Rebooted. Can not open any database or create a new one.

[benjamin]

What is the error you receive when creating new databases?

[mdevu]

There is no error message.

When you go
File > Open database
or

File > Create new database

you see the icons for each with a red mark in the top left corner.

Executing either command reverts you to the startup page with no error messge 

[mdevu]

Disabled Windows 7 Firewall and can now access database,